While rapamycin has adverse side effects in humans who take it daily for immunosuppression, recent research has found that pulse dosing, perhaps once a week, may confer most of the anti-aging benefits without any adverse side effects. Mikhail Blagosklonny, a doctor and scientist at the Roswell Park Cancer Institute in New York, has been the most notable and vocal advocate of rapamycin to extend human lifespan. Rapamycin, a drug used as an immunosuppressant in the treatment of organ transplant patients, may be the most potent life-extension drug currently available, and the practice of rapamycin anti-aging medicine is just getting started.
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